Background. Tretinoin has been shown to improve photoaged skin. This study was designed to evaluate the efficacy and tolerability\nof a 5% retinoic acid peel combined with microdermabrasion for facial photoaging. Materials and Methods. Forty-five patients,\naged 35ââ?¬â??70, affected by moderate-to-severe photodamage were enrolled in this trial. All patients received 3 sessions of full facial\nmicrodermabrasion and 3 sessions of either 5% retinoic acid peel or placebo after the microdermabrasion. Efficacy was measured\nusing the Glogau scale. Patients were assessed at 2 weeks and 1, 2, and 6 months after treatment initiation. Results. The mean Ã?± SD\nage of participants was 49.55 Ã?± 11.61 years, and the majorities (73.3%) were female. Between 1 month and 2 months, participants\nreported slight but statistically significant improvements for all parameters (
Loading....